Understanding the
heart begins with understanding its function.

First discovered in 1963, MCG is a medical imaging technique that measures the magnetic fields naturally generated by the electrical activity of the heart. The unique sensitivity of MCG enables physicians to detect and characterize even the smallest alterations in cardiac electrophysiology that may arise as a result of heart disease.

Timeline of MCG

Overcoming barriers
to clinical utility.

Unfortunately, early versions of MCG devices were too bulky, expensive, and finicky to be useful in clinical practice, limiting their adoption to mostly academic institutions.

Genetesis’ CardioFlux MCG resolves these barriers by integrating the latest advances in sensing technology and machine learning to produce an MCG device requiring only a standard-sized room (without magnetic shielding) and a single standard outlet.

Our Clinical Trials

Measuring & mapping the heart's magnetic field

The most well-known output of MCG is the magnetic field map (MFM). An MFM appears as a 3D surface with peaks and valleys that characterize magnetic field intensity and direction. The heart’s electrical conduction gives rise to the net current vector and corresponding magnetic dipoles, defined by the most positive and most negative magnetic field values captured.

Interpreting MFMs to detect potential abnormalities

Normal MFM

During ventricular repolarization, a normal MFM should exhibit a singular current pattern that results in a single positive and negative pole, each appearing distinct and clearly defined.

Abnormal MFM

In patients with functional ischemia, a multipolar pattern will often appear during repolarization, indicating heterogeneity and alterations in the amplitude and rate of action potentials in affected tissue.


MCG is sensitive to ischemia earlier than other modalities.

MCG is believed to detect cardiac dysfunction early on in the ischemic cascade because of its sensitivity to changes in ion conduction and action potential. One of the major advantages of MCG is that magnetic fields are not distorted as they travel through tissue, unlike electrical currents that are directly measured using EKG. Additionally, MCG has demonstrated higher sensitivity to tangential and vortex currents which provide ischemia-rich information. 

MCG began with CAD

Several decades of research and multiple peer-reviewed studies around the world have clearly proven MCG’s ability to diagnose coronary artery disease (CAD), where MCG has demonstrated accuracy rivaling - and in some cases, even outperforming - current standard of care stress testing.

Genetesis takes the torch

Emerging data from a new study conducted by Genetesis and presented at the ESC 2022 meeting in Barcelona demonstrated how MCG may have the ability to diagnose coronary microvascular dysfunction (CMD) in patients with ischemia and non-obstructive arteries (INOCA), a disease understood to be “invisible” to most forms of clinically available stress testing.

Opportunities for clinical impact.

Like other modern imaging technologies, MCG has the potential to be far more than a single-purpose diagnostic. Here are three major areas where MCG has been and continues to be explored.


Direct Diagnosis

MCG’s ability to identify functional ischemia earlier than conventional imaging may meaningfully improve the non-invasive diagnosis of various functionally significant diseases, like coronary artery disease, microvascular dysfunction, or myocardial infarction.

Patient Monitoring

MCG may be useful in patients who require ongoing monitoring, such as in patients who undergo revascularization (e.g., stent, CABG) or medication management (e.g., statins).

Fetal Observation

Fetal MCG can more accurately detect the cardiac signal of unborn children, providing information about fetal heart rate and rhythm to aid in the detection of potential complications or fetal distress.

MCG was never intended to
be a single-purpose diagnostic.